RESUMO
An outbreak of measles due to secondary vaccine failure prompted this investigation into the prevalence of measles antibody in children. We studied 608 children in 7 different age groups: 6, 9, 14 and 18 months and 6, 10 and 15 years. Children in the 2 youngest groups received no vaccination; the rest were vaccinated at 9 months and 15 months. The 15-year-old age group received an additional vaccination. Transplacental measles antibody (Ab) decreased from 10.0% at 6 months to 0% at 9 months. Measles Ab was positive in 52.9% (14 months), 89.4% (18 months), 60.8% 96 years), 45.0% (10 years) and 96.8% (15 years). To increase Ab levels, a booster vaccination is recommended, administered either with the second DPT booster or at pre-high school age.
Assuntos
Anticorpos Antivirais/sangue , Surtos de Doenças/estatística & dados numéricos , Imunoglobulina G/sangue , Vírus do Sarampo/imunologia , Sarampo/epidemiologia , Sarampo/prevenção & controle , Adolescente , Distribuição por Idade , Criança , Pré-Escolar , Surtos de Doenças/prevenção & controle , Ensaio de Imunoadsorção Enzimática , Feminino , Humanos , Imunização Secundária , Incidência , Lactente , Transmissão Vertical de Doenças Infecciosas/estatística & dados numéricos , Irã (Geográfico)/epidemiologia , Masculino , Sarampo/sangue , Sarampo/imunologia , Sarampo/transmissão , Determinação de Necessidades de Cuidados de Saúde , Vigilância da População , Prevalência , Estudos Soroepidemiológicos , Fatores Socioeconômicos , Saúde da População Urbana/estatística & dados numéricos , VacinaçãoRESUMO
An outbreak of measles due to secondary vaccine failure prompted this investigation into the prevalence of measles antibody in children. We studied 608 children in 7 different age groups: 6, 9, 14 and 18 months and 6, 10 and 15 years. Children in the 2 youngest groups received no vaccination; the rest were vaccinated at 9 months and 15 months. The 15-year-old age group received an additional vaccination. Transplacental measles antibody [Ab] decreased from 10.0% at 6 months to 0% at 9 months. Measles Ab was positive in 52.9% [14 months], 89.4% [18 months], 60.8% 96 years], 45.0% [10 years] and 96.8% [15 years].To increase Ab levels, a booster vaccination is recommended, administered either with the second DPT booster or at pre-high school age
